RHB-101 « RedHill Biopharma Ltd



RHB-101

RHB-101 is a once daily controlled release proprietary formulation of Carvedilol. Carvedilol is marketed under various trade names including GSK’s Coreg®.

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RHB-101 was licensed from Egalet a/s (a private Danish company) in November 2009. As carvedilol, RHB-101 is a β-adrenergic blocking agent with α1-blocking activity and is planned to be indicated for the treatment of heart failure, left ventricular dysfunction (following myocardial infarction) and hypertension.

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Several clinical PK studies were conducted with RHB-101. RedHill plans to submit a New Drug Application (NDA) in the U.S. and a Marketing Authorization Application (MAA) in Europe.