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RHB-101 (Cardio)

RHB-101 is a once daily controlled release proprietary formulation of Carvedilol. 

Carvedilol is marketed under various trade names including GSK’s Coreg®.

RHB-101 was licensed from Egalet a/s, a private Danish company, in November 2009.

As carvedilol, RHB-101 is a β-adrenergic blocking agent with α1-blocking activity and is planned to be indicated for the treatment of heart failure, left ventricular dysfunction (following myocardial infarction) and hypertension.

Several clinical PK studies were conducted with RHB-101. RedHill plans to submit a New Drug Application (NDA) in the U.S. and a Marketing Authorization Application (MAA) in Europe.

Commercial Products Development Pipeline Pipeline Overview RHB-105 (Talicia®) RHB-104 (GI/Inflammation) RHB-204 (NTM) RHB-102 (Bekinda®) (GI) RHB-106 (GI) ABC294640 (Opaganib, Yeliva®) RHB-107 (Oncology/GI) Expanded Access Program

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